Organic Chemistry 2nd Edition by Jonathan Clayden, ISBN-13: 978-0199270293
[PDF eBook eTextbook]
1264 pages
Publisher: Oxford University Press; 2 edition (May 4, 2012)
Language: English
ISBN-10: 0199270295
ISBN-13: 978-0199270293
Inspiring and motivating students from the moment it published, Organic Chemistry has established itself in just one edition as the student’s choice of an organic chemistry text.
The second edition refines and refocuses Organic Chemistry to produce a text that is even more student-friendly, coherent, and logical in its presentation than before.
Like the first, the second edition is built on three principles:
– An explanatory approach, through which the reader is motivated to understand the subject and not just learn the facts;
– A mechanistic approach, giving the reader the power to understand compounds and reactions never previously encountered;
– An evidence-based approach, setting out clearly how and why reactions happen as they do, giving extra depth to the reader’s understanding.
The authors write clearly and directly, sharing with the reader their own fascination with the subject, and leading them carefully from topic to topic. Their honest and open narrative flags pitfalls and misconceptions, guiding the reader towards a complete picture of organic chemistry and its universal themes and principles.
Table of contents:
Content: 1. What is organic chemistry? ; 2. Organic structures ; 3. Determining organic structures ; 4. Structure of molecules ; 5. Organic reactions ; 6. Nucleophilic addition to the carbonyl group ; 7. Delocalization and conjugation ; 8. Acidity, basicity, and pKa ; 9. Using organometallic reagents to make C-C bonds ; 10. Nucleophilic substitution at the carbonyl group ; 11. Nucleophilic substitution at C=O with loss of carbonyl oxygen ; 12. Equilibria, rates and mechanisms ; 13. 1H NMR: Proton nuclear magnetic resonance ; 14. Stereochemistry ; 15. Nucleophilic substitution at saturated carbon ; 16. Conformational analysis ; 17. Elimination reactions ; 18. Review of spectroscopic methods ; 19. Electrophilic addition to alkenes ; 20. Formation and reactions of enols and enolates ; 21. Electrophilic aromatic substitution ; 22. Conjugate addition and nucleophilic aromatic substitution ; 23. Chemoselectivity and protecting groups ; 24. Regioselectivity ; 25. Alkylation of enolates ; 26. Reactions of enolates with carbonyl compounds: the aldol and Claisen reactions ; 27. Sulfur, silicon and phosphorus in organic chemistry ; 28. Retrosynthetic analysis ; 29. Aromatic heterocycles 1: structures and reactions ; 30. Aromatic heterocycles 2: synthesis ; 31. Saturated heterocycles and stereoelectronics ; 32. Stereoselectivity in cyclic molecules ; 33. Diastereoselectivity ; 34. Pericyclic reactions 1: cycloadditions ; 35. Pericyclic reactions 2: sigmatropic and electrocyclic reactions ; 36. Participation, rearrangement and fragmentation ; 37. Radical reactions ; 38. Synthesis and reactions of carbenes ; 39. Determining reaction mechanisms ; 40. Organometallic chemistry ; 41. Asymmetric synthesis ; 42. Organic chemistry of life ; 43. Organic chemistry today
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